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HLA Test Cost in India

The HLA B27 test cost in India starts at 60-70 USD. The HLA B27 test price in India changes as per the geographical location and brand of the laboratory. Human leukocyte antigens (HLAs) are proteins commonly found in white blood cells.

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    HLA Test: Purpose, Procedure, Interpretation

    HLA typing is a type of genetic test that is used to determine specific differences in a person’s immune system. The procedure is crucial for determining who can safely donate bone marrow, cord blood, or an organ to a transplant recipient. Although HLA stands for human leukocyte antigen, it is typically always abbreviated to HLA. HLA matching is another term for HLA typing.

    What is the HLA Typing Test?

    Human leukocyte antigen (HLA) typing is a method to determine how closely a transplant recipient’s tissues match their potential donor’s tissues. Human leukocyte antigen (HLA) typing is used to match patients and donors for bone marrow or cord blood transplants. 

    HLA are proteins, or markers, found on most cells in your body. HLA typing is a medical test used to assess whether organ and blood marrow donors are suitably and safely matched to a transplant recipient.
    HLA testing matches organ and tissue transplant recipients with compatible donors. Different kinds of transplants require different levels of matching between donors and recipients.

    Human leukocyte antigen (HLA) typing is a method to determine how closely a transplant recipient’s tissues match their potential donor’s tissues.
    HLA typing is a medical test used to assess whether organ and blood marrow donors are suitably and safely matched to a transplant recipient.

    What is an HLA match?

    Human leukocyte antigens are proteins you inherit from your parents. Your HLA proteins, or markers, make up your HLA type. Your immune system uses HLA markers to recognize which cells belong in your body and which do not.
    An HLA match is the number of HLA markers that any two people have in common. HLA matching is usually based on either eight or 10 HLA markers. The more markers two people share, the better the match.

    Who is likely to be an HLA match?

    The most likely place to find an HLA match is among siblings who have the same mother and father.
    You have a 25-per cent chance of inheriting the same HLA markers as your sibling (an HLA-identical match). You have a 50-percent chance of inheriting half of the same HLA markers as your sibling (a haploidentical match). You have a 25-per cent chance of inheriting none of the HLA markers your sibling inherited. 

    How do we find the best HLA match?

    When a doctor recommends a bone marrow transplant, the patient, their siblings and sometimes their parents will have samples (a blood draw or a swab of the inside of the cheek) collected for HLA typing. These will be tested in a lab.
    If a relative is an identical match, the lab will do further testing to be absolutely sure that they are the best match possible. If no sibling is a good match, the doctor may ask to test other family members. Your parents and children have the next best chance of being closely matched with you.

    How Are HLA Genes Inherited?

    Biological parents always share half of their HLA proteins with their children. This is also called a “half match.” Conversely, a child always is a half match with their parents.
    A child would share half of the colours on his cells with each of his parents. Siblings who share both parents are most likely to be an identical HLA match. Such siblings have a 1 in 4 chance of being a perfect HLA match (with perfectly matching coloured strings).
    Because the HLA genes are located close together in your DNA, they are usually inherited as a group. You inherit a whole set of colours, not just one individual colour at a time.
    Your HLA type is composed of the set of HLA genes you inherit from your mother and the HLA genes you inherit from your father. In our analogy, the HLA genes contain information about the “colour of the strings” your cells will have.

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      Is HLA Typing the Same as Blood Typing?

      No. HLA typing is much more complicated than blood typing because there are many more HLA markers that make a person’s cells unique. There are only eight basic blood types, and many people can safely receive more than one type of blood. To receive only blood from a person, you do not need to be an HLA match, because HLA is not present in red blood cells.

      How Is It Performed?

      Allele-level resolution data at primary HLA typing is ideal for most histocompatibility testing laboratories. Many high-throughput molecular HLA typing approaches are unable to determine the phase of observed DNA sequence polymorphisms, leading to ambiguous results.
      The use of higher-resolution methods is often restricted due to cost and time limitations. Here we report on the feasibility of using Pacific Biosciences’ Single-Molecule Real-Time (SMRT) DNA sequencing technology for high-resolution and high-throughput HLA typing.
      This method has the potential to revolutionize the field of HLA typing. The clinical impact of achieving this level of resolution HLA typing data is likely to be considered, particularly in applications such as organ and blood stem cell transplantation where matching donors and recipients for their HLA is of utmost importance. 

      Why is HLA Typing (A, B, C, DP, DQ, DR) Test Done?

      The test is done for more accurate characterization of alleles that may benefit better identification of donor and recipient compatibility in those undergoing organ transplant. HLA through NGS offers typing of all 6 loci giving 12 point matching till field 3.This helps reduce or avoid organ mismatch and bring down the rejection rates. May also help reduce the cases of post organ transplant infections.

      What if the results are High/ Low?

      Based on the cross matching between the donor and recipient the HLA typing result is determined. Depending upon the organ to be transplanted, doctors will recommend the matching score out of the possible 12 points.

      What is the High Resolution HLA Typing (A, B, C, DP, DQ, DR) test also known as?

      HLA typing test
      High Resolution HLA typing
      What does HLA Typing (A, B, C, DP, DQ, DR) measure?
      The test helps more accurately characterize HLA alleles up to 6 loci in the donor and recipient using the NGS based technology.

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        BLK_Super_Specialty_Hospital

        BLK-Max Hospital

        Number of beds: 700
        ICU Beds:               175
        Airport Distance: 13 Km

        About Hospital:

        • BLK Super Speciality Hospital was established by Dr. B.L. Kapur  in 1959. It was inaugurated by the then Prime Minister of India, Pandit Jawahar Lal Nehru.
        • BLK Super Speciality Hospital was established by Dr. B.L. Kapur  in 1959. It was inaugurated by the then Prime Minister of India, Pandit Jawahar Lal Nehru.
        • BLK has a unique combination of the best in class technology, put to use by the best names in the professional circles to ensure world-class health care to all patients.

        indraprastha apollo hospital

        Indraprastha Apollo Hospital

        No. of beds: 900
        ICU Beds:     262
        Airport:        20kms

        Brief About:

        • Indraprastha Apollo Hospital is a flagship hospital of India’s foremost healthcare groups,the Apollo Group. It is a highly renowned multi-speciality facility that offers tertiary and quaternary care services to domestic and international patients.
        • The 900 bedded hospital is outfitted with the most modern technology for diagnostics as well as therapeutic purposes.
        • A team of highly trained medical professionals work under all the 52 specialities at the hospital.

        Max Hospital Saket3

        Max Super Specialist Hospital Saket

        Number of beds:   500
        ICU Beds:                 267
        Airport Distance: 13 KM

        Brief About:

        • Max Super Speciality Hospital at Saket is one of the topmost healthcare service
        • Providers in India. The multi-super speciality hospital has a capacity of over 500 beds, 250 functional beds. It is equipped with state-of-the-art facilities, advanced technologies.
        • With the help of over 300 leading specialist Doctors, strong nursing staff, and state-of-the-art innovative medical tools.

        Artemis Hospital

        Artemis Hospital Gurgaon

        Number of beds:  600
        ICU Beds:                185
        Airport Distance: 19 Km

        Brief About:

        • Artemis Hospital, established in 2007, spread across 9 acres, is a 600plus bed; state-of-the-art multi-speciality hospital located in Gurgaon, India.
        • Artemis Hospital is the first JCI and NABH accredited hospital in Gurgaon.
        • Designed as one of the most advanced hospitals in India, Artemis provides a depth of expertise in the spectrum of advanced medical & surgical interventions, a comprehensive mix of inpatient and outpatient services.

        Medanta-Hospital-Gurgaon

        Medanta The Medicity Hospital

        Number of beds:  1250
        ICU Beds:                300
        Airport Distance: 18 KMs

        Brief About:

        • Medanta – The Medicity is amongst India’s largest and most renowned multi-super speciality healthcare centre with 1250 beds, 29 super speciality units and more than 800 accomplished doctors.
        • Supported by state-of-art infrastructure, all the departments in the hospital are fully equipped with cutting-edge technology, modular Operation Theatre and modernized monitoring systems in ICUs.
        • The panel of doctors from Medanta, headed by A.S.Soin performed the first successful intestinal transplant in India.

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          We offers these Services

          • Providing a doctor’s opinion and proper quotation
          • Selecting the best hospital and doctor as per your case
          • Arranging a call with the doctor (if the case required)
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          • Arranging video consultation with specialist doctor if case requires

          FMRI

          Fortis Memorial Research Institute

          Number of beds:    1000
          ICU Beds:                  298
          Airport Distance:  17 KMs

          Brief About:

          • Fortis Memorial Research Institute was established in 2001.
          • It is an outstanding multi-speciality quaternary care hospital,having the top-notch infrastructure, advanced equipment, highly qualified and experienced medical professionals and super sub-specialists.
          • Fortis Hosptial Gurgaon is an advanced centre of excellence in Robotic Surgery, Neurosciences, Oncology, Renal Sciences, BMT, Organ Transplants, Orthopaedics, Cardiac Sciences and Obstetrics & Gynaecology.

          Sanar International Hospital Gurugram, Delhi NCR

          Sanar International Hospital

          Number of beds:   130
          ICU Beds:                  35
          Airport Distance:  20 Km

          About Hospital:

          • Sanar International Hospital was established in 2018.
          • Sanar International Hospital founded by Mr. Naresh Kapoor.
          • Sanar International Hospital offers comprehensive advanced surgical care in specialties like Cancer, Heart, Blood and Marrow Transplant, Lung, Liver, and Neurosciences along with other major departments with advanced state-of-the-art facilities.

          W Pratiksha Hospital

          W Pratiksha Hospital

          Number of beds: 110
          ICU Beds:                 31
          Airport Distance: 19 KMs

          About Hospital:

          • Established in 1995, W Pratiksha Hospital is a 110+ bedded flagship hospital of the Pratiksha group.
          • W Pratiksha Hospital in Gurgaon, the flagship hospital of Pratiksha Group is a one-of-its-kind facility in Gurgaon that brings to you 30 years of experience.
          • The hospital has treated more than 25,000 people In 2018.

          aakash hospital

          Aakash Health Care Delhi

          Number of beds:  230
          ICU Beds:                70
          Airport Distance: 10 Km

          About Hospital:

          • Aakash Healthcare Super Speciality Hospital is a tertiary care facility, with 15 Dialysis, and 70 Critical care beds for treating the most complex cases in the National Capital Region (NCR) of Delhi, Dwarka.
          • The hospital is equipped with state of the art infrastructure, latest technology, competent clinicians and compassionate staff.
          • Aakash Healthcare Super Specialty Hospital is known for its leading care in Orthopaedic and Joint replacement surgery.

          Accord Superspeciality Hospital Faridabad Delhi NCR

          Accord Superspeciality Hospital

          Number of beds:   380+
          ICU Beds:                  41
          Airport Distance:  46 Km

          About Hospital:

          • The story of Accord began with the thought of leveraging the new age technology with the healthcare infrastructure to serve the patients, rightly, effectively, and timely.
          • Accord Superspeciality Hospital (A Unit Of SCL Healthcare Pvt. Ltd) is India’s first smart hospital and one of the first of its kind in the world.
          • Accord Superspeciality Hospital aims at providing technologically advanced healthcare services to international patients who are looking out for medical tourism in India.

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            We offers these Services

            • Providing a doctor’s opinion and proper quotation
            • Selecting the best hospital and doctor as per your case
            • Arranging a call with the doctor (if the case required)
            • Visa assistance, Providing Visa Invitation Letter (VIL)
            • Providing full guidance how to get Visa from your country
            • Providing total cost including treatment, air tickets, accommodation, and food
            • Assitance to book flight ticket from your country
            • Arranging airport pick up/ drop
            • Providing professional language interpreter
            • Booking accommodation and guest house as per your budget/ prefrence
            • Providing help in money exchanging
            • Providing local sim card
            • Arranging video consultation with specialist doctor if case requires
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